4E-BP1 (phospho-Thr37/46) rabbit pAb

簡要描述：SourceRabbitApplicationsWB,IHC,ELISAReactivityHuman,Mouse,RatDilutionWB:1:500-1:2000

產(chǎn)品型號：
廠商性質(zhì)：生產(chǎn)廠家
更新時間：2025-12-25
訪問量：333

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產(chǎn)品分類

CLASSIFICATION

Primary Antibodies

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詳細(xì)介紹

Source

Rabbit
Applications

WB,IHC,ELISA
Reactivity

Human,Mouse,Rat
Dilution

WB: 1:500 - 1:2000. IHC: 1:100 - 1:300. ELISA: 1:10000. Not yet tested in other applications.
Storage

-20°C/1 year
Specificity

Phospho-4E-BP1 (S64) Polyclonal Antibody detects endogenous levels of 4E-BP1 protein only when phosphorylated at S64.
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

The antiserum was produced against synthesized peptide derived from human 4E-BP1 around the phosphorylation site of Ser64. AA range:30-79
Uniprot No

Q13541
Alternative names

EIF4EBP1; Eukaryotic translation initiation factor 4E-binding protein 1; 4E-BP1; eIF4E-binding protein 1; Phosphorylated heat- and acid-stable protein regulated by insulin 1; PHAS-I
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

eukaryotic translation initiation factor 4E binding protein 1(EIF4EBP1) Homo sapiens This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. [provided by RefSeq, Jul 2008],
Other

EIF4EBP1, Eukaryotic translation initiation factor 4E-binding protein 1; Phosphorylated heat- and acid-stable protein regulated by insulin 1
Mol.Wt (Da)

12449
Concentration

1 mg/ml

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4E-BP1 (phospho-Thr37/46) rabbit pAb

Source

Applications

Reactivity

Dilution

Storage

Specificity

Source/Purification

Immunogen

Uniprot No

Alternative names

Form

Clonality

Isotype

Background

Other

Mol.Wt (Da)

Concentration

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